Jiahuai Han, Ph.D.

Professor, School of Life Sciences at Xiamen University
Distinguished Professor of Chinese “Thousand  Talents Program”
Distinguished Professor of Chinese “Chang Jiang  Scholars Program”
Elected Member, the Chinese Academy of  Sciences 

Administrative positions:
           Dean, Faculty of Medicine and Life Sciences,  Xiamen University, China
           Director, State Key Laboratory of Cellular  Stress Biology
           Director, Innovation Center for Cell Signaling  Network
           Director, Laboratory Animal Center, Xiamen  University, China
           Vice President, Xiamen University, Xiamen,  China.
           Vice President, Chinese Society for Cell  Biology.

Education:
           B.S., Beijing University (Peking  University), China, 1982. Specialty in Biochemistry
           M.S., Beijing University, China, 1985.  Specialty in Protein Chemistry
           Ph.D., University of Brussels  (University Libre de Bruxelles), Belgium, 1990. Specialty in Molecular Biology

Research and Professional Experience:
           1987 – 1992  Research Fellow, Department of Internal  Medicine and Howard Hughes Medical   Institute, University of Texas Southwestern Medical Center at Dallas,  Dallas, Texas, USA
           1992 – 1993  Research Associate, Department of Immunology,  The Scripps Research Institute, La Jolla, California, USA
           1993 – 1996  Assistant Member (Assistant Professor),  Department of Immunology, The Scripps Research Institute, La Jolla, California,  USA
           1996 – 2004  Associate Professor, Department of  Immunology, The Scripps Research Institute, La Jolla, California, USA
           2004 – 2007  Professor, Department of Immunology, The  Scripps Research Institute, La Jolla, California, USA
           2007 – Present   Adjunct Professor (Professor of Immunology),  Department of Immunology, The Scripps Research Institute, La Jolla, California,  USA
           2007 – Present  Professor, School of Life Sciences, Xiamen  University, China
       

Awards:
           Jean Stas Award (Belgium), 1991
           Established Investigatorship Award  (American Heart Association), 1995
           Distinguished Young Scholar (B class,  National Science Foundation of China), 2001
           Chang Jiang Scholar (The Ministry of  Education, China), 2002
           Lu Jiaxi Excellent Mentor (Lu Jiaxi  Science and Education Foundation), 2009
           YaoMingKangDe Life Science and Chemistry  Award (1st Prize, Wuxi Pharma), 2009
           Chang Jiang Scholar Achievement Award  (The Ministry of Education of China), 2009
           First Prize in Natural Science Research  (The Ministry of Education of China), 2011
           Voted one of the ten most innovative  scientists in China (Chinese Science Net), 2011
           Overseas Chinese Contribution Award  (All-China Fed. Returned Overseas Chinese), 2012
           Nationwide Outstanding Doctoral  Dissertation, Mentor Award (The Ministry of Education of China), 2012
           The sixth Tan Jiazhen Life Science  Achievement Award (Tan Jiazhen Award Foundation), 2013
           The Second Prize of National Natural  Science Award (The State Council, China), 2013
           Outstanding scientific and technological  expert in Fujian (Fujian province government, China), 2014
           Outstanding scientific and technological  expert in China (China Association for Science and Technology), 2014
           Sanofi- Cell Research Outstanding Paper  Prize, 2014

Professional Society Members for:
           American Society for Molecular Biology  and Biochemistry
           The American Association of  Immunologists
           American Society for Microbiology
           International Society of Endotoxin
           International Communication Committee of  Chinese Society for Genetics
           Protein Committee of Chinese Society for  Biochemistry and Molecular Biology (Vice Chairperson)
           Chinese Society for Cell Biology (Vice  President)

Patents:
           1. Patent Number: 5,837,810
           Date  of Issue: 1998.11.17
           Name  of Patent: Polypeptides of lipopolysaccharide binding protein
           2. Patent Number: 6,010,856
           Date  of Issue: 2000.01.04
           Name  of Patent: Assay systems and methods for measuring p38 MAP kinase, and  modulators thereof
           3. Patent Number: WO 2008/057171 A2
           Date  of Issue: 2007.10.16
           Name  of Patent: 4-1BB ligand in inflammatory diseases. Polypeptides of  lipopolysaccharide binding protein
           4. Patent Number: ZL 200810071442.X
           Date  of Issue: 2008.12.10
           Name  of Patent: 聚苯乙烯-聚(苯乙烯-交替甘露糖基马来酸)及其制备方法与应用
           5. Patent Number: ZL 200810071898.6
           Date  of Issue: 2009.02.11
           Name  of Patent: 聚(苯乙烯-交替-马来酸钠)的用途
           6. Patent Number: ZL 2007 1 0009304.4
           Date  of Issue: 2012.02.01
           Name  of Patent:高唾液酸含量的免疫球蛋白抗体的制备方法与应用

Study in Han’s laboratory:
Dr. Jiahuai Han is known for the  discovery of the p38 signaling pathway, one of the most important pathways in  intracellular signaling transduction. This pathway plays important roles in  many biological processes including cell cycle regulation, cell proliferation,  cell differentiation and senescence, as well as immune reactions, development  and tumorigenesis. Another current focus of Han`s lab is molecular mechanisms  of RIP3 dependent necrosis, which is based on a recent finding in this  laboratory revealing that RIP3 is a major player in controlling programmed  necrosis.
           The research in Han’s Lab will lead to a  better understanding of the molecular mechanisms of inflammation,  cardiovascular disease and tumorigenesis, and thus provides new ideas for the  development of therapeutic intervention for these diseases.